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| Introduction           Human beings have
  always chewed or smoked various substances for pleasure, for some
  physiological effect, in connection with religious ceremonies or in an effort
  to seek a flight from reality (Hill 1952). 
  Although a few of these such as chewing gum are harmless, the majority
  of the materials that are smoked or chewed have a distinct stimulating or
  even narcotic effect.  This is due to
  the presence of various alkaloids. 
  Betel, Cola and tobacco are less immediately harmful to the user than
  opium, cannabis and coca.  The latter
  are true narcotics that contain alkaloids, which are detrimental even in
  small amounts.  If used in greater
  quantities they may lead the addict to a low state of depravity and
  degradation by causing stupor, coma, convulsions and even death.               Tobacco, Nicotiana tabacum, has become an
  important commodity worldwide even as evidence mounts of the serious side
  effects on health through its carcinogenic properties.  Tobacco is native to the Neotropical
  region, but the original wild ancestor has not been found.  It has been under cultivation for
  centuries.  The Amerindians originated
  the use of tobacco in connection with religious ceremonies.  The plant had spread over North America in
  Pre-Columbian times.  The first
  expedition of Columbus to America reported its use by the Amerindians.  Tobacco was introduced into Europe in 1156
  but at first was grown only for ornamental and medicinal values.  Jean Nicot, for whom the genus was named,
  was responsible for its development in France.  From there it spread rapidly over the rest of Europe and into
  Africa, Asia and Australia.  Smoking
  tobacco only became general after 1586, but ever since its popularity increased
  despite opposition from religious groups and governments that almost taxed tobacco
  products into extinction.  Some
  evidence suggests that tobacco was used in Ancient Egypt (see Mummy).             The slight narcotic and soothing
  properties of tobacco come from the alkaloid nicotine.  This active principle is absorbed by the
  mucous membranes of the nose and throat. 
  Essential oils and other aromatic substances that develop during the
  curing and fermentation process cause the aroma and flavor.               Out of the some 50 species of
  tobacco known, only two have gained commercial importance.  Nicotiana tabacum accounts for most
  of the production.  This was the
  native tobacco of the West Indies and most of Central and South America.  Originally a tropical plant, it has become
  adapted to cultivation in the temperate region also, and has been grown
  wherever climate permits.  There have
  been over 100 horticultural varieties developed.  Tobacco is an attractive unbranched annual growing to a height
  of 3-6 ft. with large oval, usually sessile leaves with clasping bases.  The branching inflorescence bears pink
  flowers.  The fruit is a capsule with
  many very tiny seeds.  The leaves and
  stems are covered with glandular hairs that secrete a resinous fluid and are
  sticky to the touch.             Nicotiana rustica is a
  smaller and hardier species with yellow flowers.  It is thought to have originated in Mexico and still grows wild
  in parts of North America.  This
  species was cultivated and smoked by Amerindians in Eastern North America in
  Pre-Columbian times.  It was the first
  tobacco to be grown in Virginia, but soon was replaced by N. tabacum.  However, it continued to be produced in
  Central Europe, Northern Asia and the East Indies.  This tobacco was used both for insecticidal and smoking
  purposes.               Production of
  tobacco is highly specialized.  The
  several types differ in their cultural requirements as to moisture,
  temperature, sunlight, soil and fertilizer. 
  They also differ in methods of harvesting, curing and handling.  The very tiny seeds are planted in seed
  beds and seedlings are transplanted when they are 4-6 in. high.  A light sandy loam rich in humus and well
  fertilized with potash, lime and other essential elements is desirable.  Continuous cultivation is necessary.  Tobacco that will be used as cigar
  wrappers is usually grown in the shade that insures a more uniform
  product.  Once the plants have begun
  to grow, the terminal bud is removed to direct strength to the leaves.  Frequently inferior leavs and suckers are
  also removed.  When fully ripe, as
  indicated by a change in the color of the leaves, either the entire plant is
  cut off or the leaves are harvested, one by one, as they mature in the case
  of cigar-wrapper production.                 The newly
  harvested plants or leaves are wilted and then are suspended in an inverted
  position from a framework in curing barns. 
  There are two main methods for curing:  air curing and flue curing. 
  Fire- and sun curing are less common.             Air curing is a slow process
  carried out under mostly natural conditions in well-ventilated barns.  The temperature and humidity must be
  carefully controlled.  Artificial heat
  is applied only in unfavorable weather. 
  Flue curing is a much faster process that is done in small barns with
  furnaces.  Flue-cured tobacco develops
  a typical bright yellow color, while fire curing involves drying over fires
  of charcoal or hardwood.  They are virtually
  smoked without much increase in temperature. 
  During this process they develop the odor of creosote.  This is the oldest method of curing and
  was practiced by the Amerindians.  Sun
  curing is done in the open and used mainly in Turkey and the Orient.             Curing is actually an oxidation
  process or dry fermentation, during which the leaves lose most of their water
  and green color and become tougher. 
  Certain changes in chemical composition take place that are necessary
  for the development of the desired quality. 
  Curing usually requires from 3-6 months.  Freshly cured leaves are then sorted, fermented or “sweated,”
  and aged before manufacturing.  This
  task is generally accomplished in warehouses after the leaves have been
  graded.  They are either piled up in
  large heaps or pressed into special containers.  This phase may take from six months to three years, during
  which time the aroma and odor are developed. 
  Undesirable traits are eliminated and the color and burning qualities
  are enhanced.               The proper
  grading of tobacco is a specialized task done by experienced personnel.  A single crop may yield as many as 50
  different grades.  Various “classes”
  are recognized based on the method of curing and in the case of cigar tobacco
  on the use.  The regions in which they
  are produced usually designate the types and the grades are based on use,
  texture, color, quality and other traits. 
  Seven common classes are: 
  Class 1 (Flue cured); Class 2 (Flue cured); Class 3 (Air cured Light
  and Air cured Dark); Class 4 (Cigar Filler); Class 5 (Cigar Binder); Class 6
  (Cigar Wrapper); Class 7 (Misc.).               Tobacco may be used in
  several ways.  The Amerindians used
  all snuff, chewing tobacco and smoking tobacco.  Cigars and cigarettes were later developments.  Throughout all the steps of manufacturing,
  especially in the case of cigarettes, it is necessary to maintain optimum
  moisture content.  Adding various
  hygroscopic agents such as glycerin does this.  These are called “humectants.” 
               There is a great variety of
  flavoring and conditioning materials added to make chewing and smoking
  tobacco.  These affect the taste and
  smoking qualities.  They are utilized
  as a “sauce” in which the leaves are immersed or as a “spray.”  Among them are licorice paste, sugar,
  honey, molasses, rum and tonka beans. 
  Deer’s tongue, and old favored flavoring, consists of the powdered
  leaves of Trilisa odoratissima, the wild vanilla of the southeastern
  United States.  With tonka beans the
  flavor is due to the presence of coumarin.             Blending which involves the use of
  different grades of leaf is also an important feature in manufacturing.  Perique and Latakia are common ingredients
  imported from Syria.             Snuff is made by grinding up dark
  air and fire cured leaves to a powder. 
  The poorer grades and waste are often utilized.               Chewing tobacco is made from
  Burley, a dark air cured and flue-cured tobacco.  It requires leaves that are rich in flavor, tough, gummy and
  highly absorptive to the various flavoring materials that are added.  It was an early development of the
  industry, reaching its maximum production in the early 1900’s.  Navy plug is very sweet and thick and
  consists of filler with a wrapper.             Smoking tobacco is prepared from
  heavily sauced blends of Burley, flue cured and other tobaccos or from mildly
  flavored straight Burley.  Granulated
  tobacco, the oldest type, is blended whereas the plug cuts lacking wrappers
  consist of Burley.             Cigars were manufactured before
  cigarettes and reached their height of consumption in 1930.  Formerly made by hand, they are now
  machine made except for the most expensive brands.  Three grades of tobacco are utilized:  fillers, binders and wrappers, all of which are air cured.  Tobacco for fillers must have a sweet
  pleasant flavor and burn evenly with a firm white ash.  For wrappers leaves free from flavor are
  required.  They must also be thin and
  elastic with small veins and uniform in color.  Individual leaves are picked for this.             Cigarettes require light colored
  leaves that lack gummy substances and have been either air or flue
  cured.  The most spectacular phase of
  the tobacco industry had been the development of the cigarette.  The first cigarettes were made from
  straight Virginia, flue cured or Burley tobacco.  Today properly aged leaves are used and the stems are removed by
  hand or by machine.  The moisture
  content is then increased to from 18-20 percent and the various grades are blended.  Although the actual formulas are trade
  secrets, generally cigarettes contain about 53 percent flue cured tobacco, 33
  percent Burley and 10 percent oriental and 4 percent Maryland.  The leaves are then run through a cutting
  machine where they are shredded and dried. 
  During the process the “casing” consisting of licorice, sugar,
  glycerin and various flavorings is added. 
  Cigarette paper is made from flax fiber.               Most
  production of tobacco has been in the United States.  This crop was first grown in 1612 and was
  first exported in 1618 from Jamestown. 
  From the very beginning tobacco was the backbone of the Virginia
  colony and even served as currency.  A
  culture grew up around its cultivation in tidewater Virginia which has never
  been equaled in America and which flourished for two centuries.  Following the American Revolution the
  industry declined, owing to competition of other countries and to soil
  depletion.  Gradually the industry
  moved westward from the Piedmont region of Virginia and North Carolina.  Tobacco has been grown in New England to
  some degree from the earliest days, but the crop has been important only
  since 1795.  Later specialization
  confined the industry to certain areas that were better suited to one kind of
  tobacco or the other.  The crop was
  grown commercially in 21 different states, with Kentucky and North Carolina
  producing about 60 percent of the total.              Despite the large domestic
  production a considerable quantity of tobacco has been imported, principally
  oriental types for use in cigarettes.             Other large tobacco producing
  countries included China, India, Russia, Indonesia, Brazil, Turkey, Italy and
  Japan.  Some areas, such as Cuba,
  produce an exceptionally high quality tobacco.               Tobacco extracts from low grades
  of fire- and dark air-cured leaves has been exported for making chewing
  tobacco.  Nicotiana rustica has been grown as the
  source of nicotine that is extracted for use as an insecticide.  Rutin, ordinarily obtained from buckwheat,
  is also present in tobacco leaves. 
  Nicotine sulfate had been an important insecticide until the
  development of organophosphorous compounds.               The chewing of betel nuts, or areca nuts, has been and still is widespread especially in
  Asia.  By 1952 over 400-million were
  estimated to use this product.  The
  widespread occurrence of the habit indicates its antiquity.  Herodotus first described it in 340 B.C.
  (Hill 1952).  In India, where it is
  called Pan over 100-thousand tons of the nuts are used
  annually.  There it plays an important
  role in the daily life of the inhabitants.             Betel nuts are the seeds of the
  betel nut palm, Areca catechu. 
  It is native to Malaya but is extensively cultivated wherever the nuts
  are used.  Chewing the betel nut can
  be quite a complex process.  A simple
  and most usual method involves the use of only three ingredients:  betel nuts, betel leaves and lime.  Slices are cured if the nuts are not
  wholly ripe or ripe nuts are placed in the mouth.  Then fresh leaves of the betel pepper, Piper betle, are coated with lime
  and chewed with the nuts.  This
  practices always follows dinner or is done as a breath freshener.  It has not been shown to be harmful but
  may even aid in digestion.  Often
  mixtures of the nuts with cloves, cinnamon, cardamom, nutmeg or other spices
  are utilized.  Another way of chewing
  betel involves the addition of tobacco.               Seeds of the cola tree, Cola nitida, are known as cola or
  kola nuts.  They are extensively used
  in many parts of tropical Africa for chewing.  The tree is tall with a straight trunk that can reach a height
  of over 50 ft.  It grows wild in the
  forests of tropical West Africa.  It
  is also cultivated in this region and the adjacent Sudan, and has been
  introduced into Brazil, India, Jamaica and parts of tropical Asia.  The fruit consists of star-shaped
  follicles that contain eight hard, Plano convex, fleshy seeds with a reddish
  color and the odor of roses.  These
  are marketed fresh and are usually chewed directly, although powdered nuts
  may be used.             Cola has played an important role
  in the social, religious and commercial life of the Africa natives.  It was first reported in the 12th Century.  The nuts are in great demand and the
  natives will go to considerable trouble to obtain them.  Although they have a bitter initial taste
  they leave a sweet taste in the mouth after chewing.  Using this product results in a slight
  stimulation and temporary increase in physical capacity.  It is reported to lower hunger and
  fatigue.  Cola is a very complex
  caffeine-containing product.  It not only
  contains two percent caffeine, but an essential oil and a glucoside, kolanin,
  as well. The stimulating effect of cola is in part due to the caffeine and in
  part to the kolanin that acts as a heart stimulant.  Old cola nuts tend to lose their kolanin.  Chewing cola nuts has no effect on consciousness
  and produces no known deleterious results.               Narcotic
  plants contain alkaloids that are valuable in medicine when used in
  exceedingly small amounts.  They are
  used to relieve pain, produce sleep and quiet anxiety.  However, serious physiological effects can
  easily result if they are not used with the utmost discretion.             Narcotic drugs vary markedly in
  their effects on the human body. 
  Cocaine and opium act as sedatives on mental activity and bring about
  a state of physical and mental comfort. 
  A lowering, and even suspension, of emotion and perception,
  accompanies this.  Sometimes complete
  suppression of consciousness results. 
  Cannabis, peyote, fly agaric, caapi and the solanaceous narcotics
  cause cerebral excitation and cause hallucinations, visions and
  illusions.  Their use causes intoxication
  and may be accompanied or followed by unconsciousness or other symptoms of
  abnormal brain function.  Kavakava is
  a sleep-producing drug that also produces a hypnotic state.              Coca, Erythroxylon coca, is the source of the
  drug cocaine.   Chewing or the whole
  or finely powdered leaves of the plant is an ancient custom among the
  Amerindians of the Andes and the western half of the Amazon Basin.  The plant was highly esteemed by the Incas
  who used it as an emblem of royalty (Hill 1952).  The use of coca gradually spread among the common people in
  South America and Pizarro found it in widespread use in 1553.  Some evidence suggests that cocaine was
  used in Ancient Egypt (see Mummy).             The use of coca aids one to resist
  physical and mental fatigue and to work for long periods without food or
  drink.  The average consumption is
  25-50 grams daily.  The chewing of
  coca is followed after a short period of rest by greatly stimulated
  activity.  The narcotic acts directly
  on the central nervous system, causing immediate psychic exaltation to such
  an extent that the consumer is able to forget hunger or other pain.  It is habit forming and may lead to
  physical deterioration, sickness and even death as it favors malnutrition.  The leaves are chewed with lime and the
  highly alkaline ashes of some plant, such as quinoa or cecropia leaves.  The plant is widely cultivated on the
  eastern slopes of the Andes from Colombia to Argentina.  It has also been cultivated in Java and
  India.               Opium is an ancient narcotic that
  is the dried juice that exudes from injured capsules of the Opium poppy, Papaver somniferum.  Its origin is probably Asia Minor, but it
  has spread to the West.  The Greeks,
  Romans and Egyptians and probably the early Lake Dwellers of Switzerland knew
  the drug.  It had also reached Iran,
  India and China by the 8th Century. 
  When properly utilized, opium and the alkaloids derived from it are
  valuable medicinally and have proved a blessing to humans in the relief of
  pain.  Excessive use of the drug and
  the resulting opium addiction has been and continue to be the cause of
  unbelievable suffering.  No other drug
  has caused so much corruption and tragedy. 
  In spite of every effort to stamp out the habit it has increased
  worldwide.  By 1952 it was estimated
  that 900-million people were using opium as a drug.             In India opium has usually been
  eaten and the habit was common to all classes of society.  So great has been the demand that the
  cultivation of the opium poppy continues as one of the most profitable
  industries in Pakistan and Afghanistan especially.  During earlier times of the trade, the Dutch, Portuguese and
  English openly exploited opium.  Later
  the various governments began strict regulation of its availability.  However, the recent invasion of
  Afghanistan by Western nations has led to a breakdown in curtailing the
  production of opium poppies, so that by 2003 the crop is once again spreading
  among farmers in rural areas.             In China the usual method of
  consumption was opium smoking by placing a small pellet in the bowl of a
  special pipe and inhaling the fumes. 
  In this way more morphine is said to be absorbed and the effects on
  the body may be greater.             In Europe and the United States,
  although opium, morphine, heroin, codeine and other derivatives are used as
  medicines, the smuggling and use of these narcotics are matters of utmost
  concern.               The hemp plant, Cannabis sativa, is the source of a
  textile fiber and a drying oil also yields a narcotic drug.  The dried flowering tops of females
  plants, pressed together into solid masses, constitute the official “cannabis
  indica.”  The drug can be used in
  medicine to relieve pain and in the treatment of hysteria and various nervous
  disorders.  The active principle is
  resinous in nature and contains 3-4 very powerful alkaloids.  Hemp is frequently cultivated solely as a
  drug plant.  This is especially true
  in India where hemp growing has developed to the level of a science.  The use of hemp as a narcotic is old and
  extends back to 3,000 B.C., first in China and later in India.  The plant was used by the Assyrians and
  was known to Herodotus.             Indian hemp is consumed in various
  ways.  The pure, undiluted sticky
  yellow resin, which is naturally exuded from the flowering tops of cultivated
  female plants, is known as charas or hashish.  Formerly the resin was obtained by rolling
  or treading on the leaves or by having natives run quickly through a mass of
  the plants.  The resin stuck to the
  body or clothes of the runner and was subsequently removed.  Today it is carefully pressed out of the
  flowering tops between layers of cloth and then scraped off.  Charas is smoked.  It is the most powerful form of the drug.  Bhang consists of the tops of wild plants,
  which have lower resin content in a water or milk mixture.  It is also smoked.  In America this type of hemp is known as
  "marijuana".  Ganja is a specially
  cultivated and harvested grade of hemp used for smoking and in beverages and
  candies.  It has high resin
  content.  Some evidence suggests that
  marijuana was used in Ancient Egypt (see Mummy).             Cannabis in its different forms
  can produce serious side effects for the consumer.  It causes a stupefying and hypnotic effect, accompanied by
  hallucinations, agreeable and often erotic dreams, and a general state of
  ecstasy.  Addicts while under the
  influence of the drug may show emotions of happiness, be noisy or may even
  become fanatical and commit murder. 
  However, when used in moderation it seems not to be harmful.  Prolonged use of the drug produces larger
  breasts in males.               The
  cactus, Lophophora
  williamsii,
  is the source of peyote or mescal buttons.  It is indigenous to northern Mexico and
  the southwestern United States.  It
  occurs on dry, arid plateaus in a limited area bordering on the Rio
  Grande.  This cactus has the
  appearances of a large carrot with all parts of the plant, except a button
  like top, below the ground.  These
  tops are round and flattened and are wrinkled.  They do not bear spines but little tufts of silky hairs.  Some of the buttons are very tiny while
  others may reach over 3 in. in diameter.          Peyote contains several powerful
  alkaloids with narcotic properties. 
  Amerindians of the region have used peyote for hundreds of years
  during their religious ceremonies. 
  Despite serious opposition the habit is actively practiced among some
  Amerindian groups that still maintain a sacred cult.  The buttons are chewed in either the fresh
  or dried state until they are soft. 
  They are then rolled up in the hand into little pellets, which are
  swallowed.  A beverage may also be prepared
  by boiling the buttons.  Peyote
  produces a state of ease and well-being, accompanied by visions and hypnotic
  trances.  Users find themselves in a
  world full of new sensations and pleasures. 
  Peyote also has also been used extensively for its presumed medicinal
  value as it is supposed to cure bodily ills.               Fly
  Agaric, Amanita
  muscaria,
  is known in Asia, America and Europe as one of the most poisonous fungi.  Despite this quantities of this mushroom
  are consumed in Siberia and other parts of Northeastern Asia for its
  intoxicating effect.  Dried agarics
  are chewed until soft, rolled into cylinder like pieces and swallowed.  At other times they are used in milk,
  water or the juice of berries as a beverage. 
  Using this fungus produces hallucinations and illusions accompanied by
  giddiness, involuntary words and actions and finally unconsciousness.  Two small fungi are enough to produce an
  intoxication that will last a whole day. 
  Prolonged use of this narcotic will completely shatter the nervous
  system, yet cravings for the drug among its addicts is very great.               The native people of southwestern
  Mexico were using a narcotic plant in religious ceremonies and as an
  intoxicant in Pre-Columbian times. 
  Ololiuqui is a decoction made from the seeds of Rivea corymbosa, a woody vine
  resembling morning glory.  It is still
  used primarily in Oaxaca in medicine as a means of divination and as a
  narcotic.  Ololiuqui induces a
  hypnotic sleep or coma with hallucinations and a feeling of ecstasy, but with
  no unpleasant aftereffects.                Amerindians living in the Amazon
  Basin utilize Banisteriopsis
  caapi, B.
  inebrians, B. quilensis and
  species of the genus Tetrapterys as the source of a narcotic beverage.  These plants are called caapi in Brazil, ayahusca in Peru & Ecuador and yaje in
  Columbia.  They are lianas that grow
  naturally in the virgin forests and are sometimes cultivated in native
  villages.  To prepare the beverage the
  lower part of the stem is cut off, cleaned, macerated and boiled or utilized
  as a cold decoction.  Caapi is used in
  religious ceremonies.  It produces
  visions, dreams and other mental disorientations.  It is also an excitant and induces courage.               Certain plants in the family
  Solanaceae contain alkaloids that produce disorders of the brain and
  excitation when smoked or consumed. 
  These narcotics are often responsible for some of the incomprehensible
  acts of fanatics in the East and elsewhere.             The genus Datura has been and still is
  extensively used in all the continents except Australia for its narcotic and
  hypnotic properties.  The Jimson weed, Datura stramonium, the source of the
  drug stramonium, was known as a narcotic as early as 37 A.D. (Hill
  1952).  It is still a favorite source
  for “knockout drops” in the tropics.  The Maikoa,
  D.
  arborea,
  and Datura
  sanguinea
  are
  subtropical shrubs of South America that have been used by various groups of
  the westernmost Amazon Region for their narcotic properties. The Aztecs in
  Mexico as a medicine and in their religious ceremonies used Datura innoxia.  It is still used by some of the local
  inhabitants.  Other species are also
  used elsewhere, all of them producing comparable effects, such as sense
  illusions and motor disturbances as well as senseless activities and loss of
  memory.  At least one student at the
  University of California Riverside campus literally became a vegetable after
  having experimented with a local species of Datura growing in the
  area.  This cost him his research
  assistantship and reduced him to a supervised livelihood of sweeping floors.               Kavakava, Piper methysticum, is a bushy shrub, 6-8
  ft. tall with rounded or cordate leaves. 
  It is indigenous to Fiji and other Pacific islands but is now grown
  throughout the islands of the Pacific. 
  It produces different results from those previously discussed.  The thick, knotty, grayish-green roots are
  the source.  These are dug up and the
  bark is removed.  After cleaning they
  are cut up into small pieces.  These
  pieces are chewed until they are fine and fibrous and are then placed in a
  bowl with water and allowed to ferment. 
  Formerly while the roots were being chewed the saliva was ejected into
  bowls and this constituted the beverage. 
  After straining, kavakava is a grayish-brown liquid and has a
  refreshing taste.  It is allied with
  the entire social, political and religious life of the people.  It is used as a beverage that acts as a
  sedative, a soporific and a hypnotic, bringing about pleasant dreams and
  sensations.  Excessive use may produce
  skin diseases and weaken the eyesight. 
  The active principle is a resinous substance that is stimulating in
  small amounts.     |